Botanical name: Phyllanthus niruri
PLANT NAME IN DIFFERENT LANGUAGES
Sanskrit: Tamalaki, Bhoomyamalaki, Bhoodhatri, Bahupatra.
Hindi: Jangli amli, Jaramla
Malayalam: Keezharnelli, Kirutanelli, Kizhar nelli
Keezharnelli grows 50 to 70 centimeters tall and bears ascending herbaceous branches. The bark is smooth and light green. It bears numerous pale green flowers which are often flushed with red. The fruits are tiny, smooth capsules containing seeds.
Keezharnelli is an important plant of Indian Ayurvedic system of medicine which is used for problems of the stomach, genitourinary system, liver, kidney and spleen. The plant has also been used in Brazil and Peru as a herbal remedy for kidney stones.
Keezharnelli is used to prevent the bleeding caused to viper bite.
A clinical study with Phyllanthus niruri, indicated that it may reduce the levels of urinary calcium. A subsequent study of 150 patients over a 6 month period indicated that an extract of this herb reduces the incidence of stone formation, and concluded, "Regular self-administration of P. niruri after extracorporeal shock wave lithotripsy for renal stones results in an increased stone-free rate that appears statistically significant for lower caliceal location. Its efficacy and the absolute lack of side effects make this therapy suitable to improve overall outcomes after extracorporeal shock wave lithotripsy for lower pole stones."A more recent rat study found that Phyllanthus niruri has been shown to interfere with many stages of stone formation, reducing crystals aggregation, modifying their structure and composition as well as altering the interaction of the crystals with tubular cells leading to reduced subsequent endocytosis." It is not clear that there have been any studies which conclusively found that Phyllanthus niruri was effective in treating existing stones.